Hypothalamic Gliosis Is Associated With Multiple Cardiovascular Disease Risk Factors in the Framingham Heart Study

Hypothalamic Gliosis Is Associated With Multiple Cardiovascular Disease Risk Factors in the Framingham Heart Study

Background Hypothalamic gliosis is mechanistically linked to obesity and insulin resistance in rodent models. We tested cross‐sectional associations between radiologic measures of hypothalamic gliosis in humans and clinically relevant cardiovascular disease risk factors, as well as prevalent coronar...

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Bibliographic Details
Main Authors: Justin Lo, Susan J. Melhorn, Sarah Kee, Kelsey L. W. Olerich, Alyssa Huang, Dabin Yeum, Alexa Beiser, Sudha Seshadri, Charles DeCarli, Ellen A. Schur
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiometabolic risk factors
coronary heart disease
hypertension
hypothalamic gliosis
hypothalamic inflammation
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.039463
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https://www.ahajournals.org/doi/10.1161/JAHA.124.039463

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