Bimodal onset and pan-cancer uniformity of immune-mediated liver injury: a retrospective cohort study

BackgroundImmune-mediated liver injury (IMLI) is a critical adverse event in patients treated with PD-1/PD-L1 inhibitors. The study aims to characterize the clinical heterogeneity, temporal dynamics, and immunological drivers of PD-1/PD-L1 inhibitor-associated IMLI and optimize surveillance and mana...

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Main Authors: Jiaojiao Song, Biying Xu, Lan Yu, Haiwei Fu, Binliang Wang, Mo Zhou, Yumin Hu, Yang Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1612287/full
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