Sitagliptin phosphate ameliorates chronic inflammation in diabetes mellitus via modulating macrophage polarization

AimTo investigate the effect and mechanism of Sitagliptin phosphate on inflammation and macrophage polarization in a mouse model of type 2 diabetes.MethodsIn vitro, Raw264.7 cells were cultured with a high concentration of glucose (HG) and sitagliptin phosphate (SIG). The levels of inflammatory fact...

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Bibliographic Details
Main Authors: Xiaoxia Hu, Yalong Li, Xinyue Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1544684/full
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