The effects of Fusarium graminearum cell extracts and culture filtrates on the production of paclitaxel and 10-deacetylbaccatin III in suspension cell cultures of Taxus baccata L.

The effects of Fusarium graminearum cell extracts and culture filtrates on the production of paclitaxel and 10-deacetylbaccatin III in suspension cell cultures of Taxus baccata L.

Abstract Background The genus Taxus (yew) is the sole producer of the paclitaxel with anticancer properties. The rising demand for plant-derived medicines has led to the overexploitation of various species and ecosystem degradation, which is further worsened by climate change. Taxus baccata L. cell...

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Bibliographic Details
Main Authors: Arman Kamali Dehghan, Meisam Zargar, Mahsa Bamneshin, Mohtaram Mahmoudieh, Naser Safaie, Jun-Li Yang, Mohammad Reza Naghavi
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Plant Biology
Subjects:
10-DABIII
Cell extracts
Culture filtrates
Fusarium graminearum
Suspension cell culture
Paclitaxel
Online Access:https://doi.org/10.1186/s12870-025-06230-5
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https://doi.org/10.1186/s12870-025-06230-5

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