Deletion of a polyketide synthase phoE induces monoterpenes production in ascidian-derived fungus Diaporthe sp. SYSU-MS4722

Deletion of a polyketide synthase phoE induces monoterpenes production in ascidian-derived fungus Diaporthe sp. SYSU-MS4722

Marine-derived fungi represent an underexplored source of monoterpenes, with only sporadic reports over the past two decades, making their discovery particularly challenging. Whole-genome sequencing of Diaporthe sp. SYSU-MS4722, an ascidian-derived fungus isolated from Styela plicata, identified 130...

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Main Authors: Siwen Yuan, Shitao Zhuang, Yanhong Han, Yuhang Wen, Senhua Chen, Lan Liu, Qifeng Lin, Yan Yan, Zhizeng Gao, Qilin Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
genome mining
monoterpenes
polypropionate derivatives
phomoxanthone A
antiinflammatory activity
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1593027/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1593027/full

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