Mapping immune activity in HPV-negative head and neck squamous cell carcinoma: a spatial multiomics analysis

Background Head and neck squamous cell carcinoma (HNSCC) exhibits low response rates to immunotherapies, with only about 15–25% of patients responding to monotherapy and 30–45% to combination therapy. This limited effectiveness is attributed to significant intertumor and intratumor heterogeneity, wh...

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Bibliographic Details
Main Authors: Bruno Gomes, Francesca Damiola, Nicolas Gadot, Jean-Philippe Foy, Pierre Saintigny, Natalie Zwing, Lena Voith von Voithenberg, Laurent Alberti, Sascha Michael Gabriel, Josep M Monné Rodriguez, Romi Feddersen
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/6/e011851.full
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