Prenatal inflammation exacerbates hyperoxia-induced neonatal brain injury

Prenatal inflammation exacerbates hyperoxia-induced neonatal brain injury

Abstract Background Premature born infants are at high risk to develop white matter injury (WMI). Hyperoxia and perinatal inflammation are main risk factors for preterm birth and associated brain injury. To date the majority of experimental studies have focused on isolated insults. However, clinical...

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Main Authors: Meray Serdar, Kay-Anja Walther, Markus Gallert, Karina Kempe, Stefanie Obst, Nicole Labusek, Ralf Herrmann, Josephine Herz, Ursula Felderhoff-Müser, Ivo Bendix
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Neuroinflammation
Subjects:
White matter injury
Preterm birth
Prenatal inflammation
Postnatal hyperoxia
Oligodendrocytes
Microglia
Online Access:https://doi.org/10.1186/s12974-025-03389-4
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https://doi.org/10.1186/s12974-025-03389-4

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