Haspin kinase inhibition dampens pseudorabies virus infection in vitro

Haspin kinase inhibition dampens pseudorabies virus infection in vitro

Pseudorabies virus (PRV) represents a considerable infectious threat to the swine industry in China and poses potential health risks to humans. However, there is a notable lack of specific antiviral agents aimed at combating PRV. Haspin is involved in histone phosphorylation during mitosis, while th...

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Main Authors: Lei Tan, Yong Yang, Xiaojiu Huang, Youqing Yuan, Kaixin Wang, Xiaoye Peng, Yiyan He, Yijin Wang, Lei Lei, Yingyi Chen, Deyong Duan, Naidong Wang, Yi Yang, Feiyan Dai, Cuiqing Huang, Aibing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Veterinary Science
Subjects:
pseudorabies virus
Haspin kinase
antiviral activity
CHR-6494
replication stage
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1572729/full
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https://www.frontiersin.org/articles/10.3389/fvets.2025.1572729/full

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