Bufei Jiedu Formula enhances CD40 activation and macrophage polarization to eliminate intracellular MRSA persisters

Bufei Jiedu Formula enhances CD40 activation and macrophage polarization to eliminate intracellular MRSA persisters

BackgroundIntracellular methicillin-resistant Staphylococcus aureus (MRSA) represents a complex infection in clinical practice, characterized by its refractory and recurrent nature, rendering it challenging to treat with conventional antibiotics. Bufei Jiedu Formula (BFJD) is a traditional Chinese m...

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Bibliographic Details
Main Authors: Shaoyan Zhang, Jiajun Chen, Lei Qiu, Xianwei Wu, Wei Zhou, Ruoqing Peng, Ya Feng, Rui Zhou, Xing Huang, Dingzhong Wu, Zhenhui Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
MRSA infection
persistent
intracellular
macrophage polarization
CD40
atractylenolide II
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1623182/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1623182/full

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