Fluorescent Rhein-Loaded Liposomes for In Vivo Biodistribution Study

Fluorescent Rhein-Loaded Liposomes for In Vivo Biodistribution Study

<b>Objectives:</b> This work aimed to develop and investigate liposomes incorporating Rhein (Lip-Rh) into the liposomal membrane to enhance the compound’s water solubility and oral bioavailability. <b>Methods:</b> Liposomes were produced by the thin lipid film technique, with...

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Main Authors: Silviu Iulian Filipiuc, Natalia Simionescu, Gabriela Dumitrița Stanciu, Adina Coroaba, Narcisa Laura Marangoci, Leontina Elena Filipiuc, Mariana Pinteala, Cristina Mariana Uritu, Bogdan Ionel Tamba
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceutics
Subjects:
Rhein
fluorescence imaging
liposomal Rhein
Rhein biodistribution
Rhein cytotoxicity
Online Access:https://www.mdpi.com/1999-4923/17/3/307
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