A systems‐level study reveals host‐targeted repurposable drugs against SARS‐CoV‐2 infection

A systems‐level study reveals host‐targeted repurposable drugs against SARS‐CoV‐2 infection

Abstract Understanding the mechanism of SARS‐CoV‐2 infection and identifying potential therapeutics are global imperatives. Using a quantitative systems pharmacology approach, we identified a set of repurposable and investigational drugs as potential therapeutics against COVID‐19. These were deduced...

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Bibliographic Details
Main Authors: Fangyuan Chen, Qingya Shi, Fen Pei, Andreas Vogt, Rebecca A Porritt, Gustavo Garcia, Angela C Gomez, Mary Hongying Cheng, Mark E Schurdak, Bing Liu, Stephen Y Chan, Vaithilingaraja Arumugaswami, Andrew M Stern, D Lansing Taylor, Moshe Arditi, Ivet Bahar
Format: Article
Language:English
Published: Springer Nature 2021-08-01
Series:Molecular Systems Biology
Subjects:
autophagy
SARS‐CoV‐2‐infected cell transcriptomics
syncytia formation
viral entry
viral–host interactions
Online Access:https://doi.org/10.15252/msb.202110239
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https://doi.org/10.15252/msb.202110239

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