Effects of pioglitazone on mnemonic hippocampal function: A blood oxygen level–dependent functional magnetic resonance imaging study in elderly adults

Abstract Introduction Mitochondrial dysfunction is implicated in the pathophysiology of Alzheimer's disease (AD). Accordingly, drugs that positively influence mitochondrial function are being evaluated in delay‐of‐onset clinical trials with at‐risk individuals. Such ongoing clinical research ca...

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Main Authors: Annchen R. Knodt, James R. Burke, Kathleen A. Welsh‐Bohmer, Brenda L. Plassman, Daniel K. Burns, Stephen K. Brannan, Michael Kukulka, Jingtao Wu, Ahmad R. Hariri
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
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Online Access:https://doi.org/10.1016/j.trci.2019.05.004
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