Pro-Inflammatory Properties of Salivary Gland-Derived Fibroblasts—Implications in Sjögren’s Disease

Pro-Inflammatory Properties of Salivary Gland-Derived Fibroblasts—Implications in Sjögren’s Disease

Salivary gland dysfunction is a hallmark of Sjögren’s disease (SjD). Here, we investigated the pro-inflammatory properties of salivary gland-derived fibroblasts (SGF) that were cultured from minor salivary gland (MSG) tissues of patients with SjD and controls. SGF from patients with SjD exhibited hi...

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Bibliographic Details
Main Authors: Matthias Brunner, Daniel Guggisberg, Marco Sprecher, Ondrej Pastva, Kristina Bürki, Miranda Houtman, Marco Kreuzer, Sara Andrea Krättli, Laura Jahnke, Mila Roceri, Rémy Bruggmann, Muriel Elhai, Britta Maurer, Thomas M. Marti, Caroline Ospelt, Kerstin Klein
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
Sjögren’s disease
salivary gland
inflammation
fibroblast
enhancer
bromodomain
Online Access:https://www.mdpi.com/2073-4409/14/8/558
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