Multivariate longitudinal clustering reveals neuropsychological factors as dementia predictors in an Alzheimer’s disease progression study

Abstract Dementia due to Alzheimer’s disease (AD) is a multifaceted neurodegenerative disorder characterized by various cognitive and behavioral decline factors. In this work, we propose an extension of the traditional k-means clustering for multivariate time series data to cluster joint trajectorie...

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Bibliographic Details
Main Authors: Patrizia Ribino, Claudia Di Napoli, Giovanni Paragliola, Davide Chicco, Francesca Gasparini
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BioData Mining
Subjects:
Online Access:https://doi.org/10.1186/s13040-025-00441-0
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