Investigating pulmonary inflammation and injury after progressive systemic inflammation in preterm fetal sheep

IntroductionPreterm birth and intrauterine inflammation are commonly associated with lung inflammation and remodeling. We developed a fetal inflammatory response model using increasing doses of intravenous lipopolysaccharide (LPS) to cause systemic inflammation and injury. However, the effects of an...

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Bibliographic Details
Main Authors: E. G. Vandenberg, S. B. Kelly, V. A. Zahra, H. Lu, A. Thiel, S. B. Hooper, R. Galinsky, G. R. Polglase
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1542613/full
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