Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma

Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma

This study aimed to examine HIF-2α, TWIST, and CXCR4 expression in papillary thyroid carcinoma (PTC) and assesses the association of their expression with clinicopathological indicators. HIF-2α, TWIST, and CXCR4 protein expression in 129 PTCs, 61 nodular hyperplasia, and 118 normal thyroid tissue sp...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ni Wang, Hao-Jun Luo, Guo-Bing Yin, Chao-Ran Dong, Man Xu, George G. Chen, Zhi-Min Liu
Format:	Article
Language:	English
Published:	Wiley 2013-01-01
Series:	Clinical and Developmental Immunology
Online Access:	http://dx.doi.org/10.1155/2013/589423
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Male Gender Is Associated with Lymph Node Metastasis but Not with Recurrence in Papillary Thyroid Carcinoma
by: Jiang Zhu, et al.
Published: (2022-01-01)

Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma
by: Yifan Chen, et al.
Published: (2021-01-01)

To Identify Predictors of Central Lymph Node Metastasis in Patients with Clinically Node-Negative Conventional Papillary Thyroid Carcinoma
by: Jiru Yuan, et al.
Published: (2016-01-01)

Influence of Obesity Parameters on Different Regional Patterns of Lymph Node Metastasis in Papillary Thyroid Cancer
by: Wan-Xiao Wu, et al.
Published: (2022-01-01)

Construction and validation of nomograms to predict central lymph node metastasis in clinical node-negative unilateral papillary thyroid carcinoma
by: Longqing Hu, et al.
Published: (2025-01-01)

Differential gene expression analysis of papillary thyroid carcinoma reveals important genes for lymph node metastasis
by: Wan Fahmi Wan Mohamad Nazarie, et al.
Published: (2022-07-01)

Efficacy of Shear-Wave Elastography for Detecting Postoperative Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma
by: Hye Jeong Kim, et al.
Published: (2018-01-01)

Application and Thinking of Deep Learning in Predicting Lateral Cervical Lymph Node Metastasis of Papillary Thyroid Cancer
by: Shengli SHAO, et al.
Published: (2025-01-01)

Combination of inflammatory proteins in serum can be used to diagnose papillary thyroid carcinoma with lymph node metastasis
by: Yongqin Pan, et al.
Published: (2025-01-01)

Risk Factors for Cervical Lymph Node Metastasis of Papillary Thyroid Microcarcinoma: A Single-Center Retrospective Study
by: Feng Cheng, et al.
Published: (2019-01-01)

Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node
by: Jien Shim, et al.
Published: (2018-01-01)

Correlation analysis of Hashimoto’s thyroiditis with papillary thyroid carcinoma occurrence and its central lymph node metastasis: a single center experience
by: Kang Sun, et al.
Published: (2025-02-01)

CXCR4 and Axillary Lymph Nodes: Review of a Potential Biomarker for Breast Cancer Metastasis
by: David Hiller, et al.
Published: (2011-01-01)

Axillary Lymph Node Metastasis in Papillary Thyroid Carcinoma at Early Perioperative Period: Report of a Case and Review of the Literature
by: Cumhur Arıcı, et al.
Published: (2024-10-01)

Study on the Nomogram Model Based on Dual-energy Computed Tomography for Predicting Lymph Node Metastasis in Papillary Thyroid Carcinoma
by: Bo GAO, et al.
Published: (2025-01-01)

Risk factors for mediastinal lymph node metastasis and lung metastasis in papillary thyroid carcinoma patients: who benefits from preoperative computed tomography?
by: Yoko Omi, et al.
Published: (2024-04-01)

Pretreatment level of circulating tumor cells is associated with lymph node metastasis in papillary thyroid carcinoma patients with ≤ 55 years old
by: Ming Yu, et al.
Published: (2025-01-01)

Clinical implications of Delphian lymph node metastasis in papillary thyroid carcinoma: a single-institution study, systemic review and meta-analysis
by: Bin Wang, et al.
Published: (2019-08-01)

Stimulation of TLR4 by LMW-HA Induces Metastasis in Human Papillary Thyroid Carcinoma through CXCR7
by: Shipeng Dang, et al.
Published: (2013-01-01)

Langerhans Cell Histiocytosis of the Thyroid with Multiple Cervical Lymph Node Involvement Accompanying Metastatic Thyroid Papillary Carcinoma
by: A. Bahar Ceyran, et al.
Published: (2014-01-01)

Clinical Characteristics Related to Central Lymph Node Metastasis in cN0 Papillary Thyroid Carcinoma: A Retrospective Study of 916 Patients
by: Lie-Hao Jiang, et al.
Published: (2014-01-01)

Clinicopathologic Significance of HIF-1α, CXCR4, and VEGF Expression in Colon Cancer
by: Yugang Wu, et al.
Published: (2010-01-01)

Diagnostic accuracy of ultrasound, CT and their combination in detecting cervical lymph node metastasis in patients with papillary thyroid cancer: a systematic review and meta-analysis
by: Jian Yang, et al.
Published: (2022-07-01)

B-Flow Twinkling Sign in Preoperative Evaluation of Cervical Lymph Nodes in Patients with Papillary Thyroid Carcinoma
by: Giuseppina Napolitano, et al.
Published: (2013-01-01)

Cooccurrence of Metastatic Papillary Thyroid Carcinoma and Salmonella Induced Neck Abscess in a Cervical Lymph Node
by: Jae-Myung Kim, et al.
Published: (2017-01-01)

Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-Analysis
by: Cunfu Li, et al.
Published: (2019-01-01)

Single‐cell RNA‐sequencing and spatial transcriptomic analysis reveal a distinct population of APOE− cells yielding pathological lymph node metastasis in papillary thyroid cancer
by: Guohui Xiao, et al.
Published: (2025-01-01)

Aggressive Papillary Thyroid Carcinoma Presenting with Metastasis to the Pancreas
by: Firas Warda, et al.
Published: (2022-01-01)

Late-onset metastasis of papillary thyroid carcinoma to nasopharynx
by: Yongquan Yu, et al.
Published: (2025-02-01)

Analysis of risk factors for non-sentinel lymph node metastasis in patients with sentinel lymph node-negative breast cancer
by: ZHANG Fengzhe, TONG Yiwei, CHEN Xiaosong, SHEN Kunwei
Published: (2024-09-01)

Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis
by: Jie Chen, et al.
Published: (2012-01-01)

Analysis of Predictors for Lymph Node Metastasis in Patients with Superficial Esophageal Carcinoma
by: Ruzhen Jia, et al.
Published: (2016-01-01)

Colorectal Cancer Presenting as Single Pulmonary Hilar Lymph Node Metastasis
by: Ahmed M. Habib, et al.
Published: (2018-01-01)

Clinical Study of Sentinel Lymph Node Detection to Evaluate Pelvic Lymph Node Metastasis to Determine the Prognosis of Patients with Early Cervical Cancer
by: Peipei Li, et al.
Published: (2022-01-01)

The Application of Three-dimensional Shear Wave Elastography in the Detection of Inguinal Lymph Node Metastasis in Gynecological Malignancies
by: Yuping Shen, et al.
Published: (2025-01-01)

PER3 suppresses tumor metastasis of oral squamous cell carcinoma by promoting HIF-1α degradation
by: Yaoxu Li, et al.
Published: (2025-02-01)

High-risk habitat radiomics model based on ultrasound images for predicting lateral neck lymph node metastasis in differentiated thyroid cancer
by: Han Liu, et al.
Published: (2025-01-01)

Differential Gene Expression in Primary Breast Tumors Associated with Lymph Node Metastasis
by: Rachel E. Ellsworth, et al.
Published: (2011-01-01)

Supraclavicular lymph node metastasis in esophageal carcinoma: a topic of ongoing controversy
by: Bowen Zhang, et al.
Published: (2025-01-01)

Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis
by: Yewei Jia, et al.
Published: (2025-01-01)