Temporo-spatial cellular atlas of the regenerating alveolar niche in idiopathic pulmonary fibrosis

Temporo-spatial cellular atlas of the regenerating alveolar niche in idiopathic pulmonary fibrosis

Abstract Healthy alveolar repair relies on the ability of alveolar stem cells to differentiate into specialized epithelial cells for gas exchange. In chronic fibrotic lung diseases such as idiopathic pulmonary fibrosis (IPF), this regenerative process is abnormal but the underlying mechanisms remain...

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Main Authors: Praveen Weeratunga, Bethany Hunter, Martin Sergeant, Joshua Bull, Colin Clelland, Laura Denney, Chaitanya Vuppusetty, Rachel Burgoyne, Jeongmin Woo, Tian Hu, Lee Borthwick, James Shaw, Agne Antanaviciute, Andrew Filby, Helen Byrne, Andrew Fisher, Ling-Pei Ho
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61880-1
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https://doi.org/10.1038/s41467-025-61880-1

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