A method for testing indoxacarb residues in three vegetables and the dietary risk assessment
This study focuses on the development and validation of a detection method for indoxacarb residues in three major vegetable crops, Chinese cabbage, cabbage, and tomato, which are widely cultivated worldwide. The method was rigorously validated through field trials and dietary risk assessment. A stro...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Applied Food Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772502225000691 |
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| author | Ai Liu Fengyu Li Jiacheng Ge Guodong Si Xianzheng Han Yun Gao Wenli Wang Li Su Nan Zou Wei Mu Xiaomei Li Xiuyu Pang |
| author_facet | Ai Liu Fengyu Li Jiacheng Ge Guodong Si Xianzheng Han Yun Gao Wenli Wang Li Su Nan Zou Wei Mu Xiaomei Li Xiuyu Pang |
| author_sort | Ai Liu |
| collection | DOAJ |
| description | This study focuses on the development and validation of a detection method for indoxacarb residues in three major vegetable crops, Chinese cabbage, cabbage, and tomato, which are widely cultivated worldwide. The method was rigorously validated through field trials and dietary risk assessment. A strong linear response was observed for indoxacarb at the concentrations of 0.0005 - 0.25 mg/L, with a limit of quantitation of 0.01 mg/kg. The half-life of indoxacarb ranged from 4.61 to 6.89 days in Chinese cabbage, 3.06 to 6.21 days in cabbage, and 2.28 to 3.46 days in tomato. The terminal residues were <0.01 - 0.2 mg/kg in Chinese cabbage, <0.01 - 0.15 mg/kg in cabbage, and <0.01 - 0.029 mg/kg in tomato. Dietary risk assessment revealed a low probability of long-term risk (12.9 %) associated with the consumption of these crops. Overall, the study suggests that the use of indoxacarb on these three vegetables is safe for the general population, with minimal risk even under long-term exposure. |
| format | Article |
| id | doaj-art-7d880469079c4f4094b3e1a3e19c807e |
| institution | Kabale University |
| issn | 2772-5022 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Applied Food Research |
| spelling | doaj-art-7d880469079c4f4094b3e1a3e19c807e2025-02-11T04:35:41ZengElsevierApplied Food Research2772-50222025-06-0151100759A method for testing indoxacarb residues in three vegetables and the dietary risk assessmentAi Liu0Fengyu Li1Jiacheng Ge2Guodong Si3Xianzheng Han4Yun Gao5Wenli Wang6Li Su7Nan Zou8Wei Mu9Xiaomei Li10Xiuyu Pang11School of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250021, PR China; College of Plant Protection, Shandong Agricultural University, Tai'an, Shandong 271018, PR ChinaCollege of Science, China Agricultural University, Bei'jing 10008, PR ChinaHailir Pesticides and Chemicals Group Co., Ltd., Qingdao, Shandong 266000, PR ChinaHailir Pesticides and Chemicals Group Co., Ltd., Qingdao, Shandong 266000, PR ChinaHailir Pesticides and Chemicals Group Co., Ltd., Qingdao, Shandong 266000, PR ChinaResearch Center of Pesticide Environmental Toxicology, Shandong Agricultural University, Tai'an, Shandong 271018, PR ChinaResearch Center of Pesticide Environmental Toxicology, Shandong Agricultural University, Tai'an, Shandong 271018, PR ChinaResearch Center of Pesticide Environmental Toxicology, Shandong Agricultural University, Tai'an, Shandong 271018, PR ChinaCollege of Plant Protection, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; Research Center of Pesticide Environmental Toxicology, Shandong Agricultural University, Tai'an, Shandong 271018, PR ChinaCollege of Plant Protection, Shandong Agricultural University, Tai'an, Shandong 271018, PR China; Research Center of Pesticide Environmental Toxicology, Shandong Agricultural University, Tai'an, Shandong 271018, PR ChinaSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250021, PR China; Corresponding authors.School of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250021, PR China; Corresponding authors.This study focuses on the development and validation of a detection method for indoxacarb residues in three major vegetable crops, Chinese cabbage, cabbage, and tomato, which are widely cultivated worldwide. The method was rigorously validated through field trials and dietary risk assessment. A strong linear response was observed for indoxacarb at the concentrations of 0.0005 - 0.25 mg/L, with a limit of quantitation of 0.01 mg/kg. The half-life of indoxacarb ranged from 4.61 to 6.89 days in Chinese cabbage, 3.06 to 6.21 days in cabbage, and 2.28 to 3.46 days in tomato. The terminal residues were <0.01 - 0.2 mg/kg in Chinese cabbage, <0.01 - 0.15 mg/kg in cabbage, and <0.01 - 0.029 mg/kg in tomato. Dietary risk assessment revealed a low probability of long-term risk (12.9 %) associated with the consumption of these crops. Overall, the study suggests that the use of indoxacarb on these three vegetables is safe for the general population, with minimal risk even under long-term exposure.http://www.sciencedirect.com/science/article/pii/S2772502225000691QuEChERS UPLC-MS/MSIndoxacarbNational estimated daily intakesTerminal residuesDietary risk assessment |
| spellingShingle | Ai Liu Fengyu Li Jiacheng Ge Guodong Si Xianzheng Han Yun Gao Wenli Wang Li Su Nan Zou Wei Mu Xiaomei Li Xiuyu Pang A method for testing indoxacarb residues in three vegetables and the dietary risk assessment Applied Food Research QuEChERS UPLC-MS/MS Indoxacarb National estimated daily intakes Terminal residues Dietary risk assessment |
| title | A method for testing indoxacarb residues in three vegetables and the dietary risk assessment |
| title_full | A method for testing indoxacarb residues in three vegetables and the dietary risk assessment |
| title_fullStr | A method for testing indoxacarb residues in three vegetables and the dietary risk assessment |
| title_full_unstemmed | A method for testing indoxacarb residues in three vegetables and the dietary risk assessment |
| title_short | A method for testing indoxacarb residues in three vegetables and the dietary risk assessment |
| title_sort | method for testing indoxacarb residues in three vegetables and the dietary risk assessment |
| topic | QuEChERS UPLC-MS/MS Indoxacarb National estimated daily intakes Terminal residues Dietary risk assessment |
| url | http://www.sciencedirect.com/science/article/pii/S2772502225000691 |
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