Structure of the complex of C1q-like 3 protein with adhesion-GPCR BAI3

Abstract The adhesion-GPCR Brain-specific Angiogenesis Inhibitor-3 (BAI3) plays a crucial role in organizing synapses in the brain. However, how BAI3 engages one of its ligands, the C1q-like proteins (C1qls), remains largely unexplored. Here, we present the single-particle cryo-electron microscopy (...

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Bibliographic Details
Main Authors: Yi Miao, Haoqing Wang, Kevin M. Jude, Jie Wang, Jinzhao Wang, Marius Wernig, Thomas C. Südhof
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08112-w
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