Solitary Fibrous Tumor of Neck Mimicking Cold Thyroid Nodule in 99m Tc Thyroid Scintigraphy
A 68-year-old man had a rapidly growing, painless neck mass, thought to be nodular goiter. Ultrasonography showed a giant, heterogeneous mass occupying the middle and superior poles and protruding outside of the left thyroid lobe. The results of the thyroid function tests were normal. Thyroid scinti...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/805745 |
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| author | Oya Topaloglu Bekir Ucan Taner Demirci Muyesser Sayki Arslan Guleser Saylam Evrim Onder Sinan Gultekin Alper Dilli Mustafa Sahin Erman Cakal Mustafa Ozbek Tuncay Delibasi |
| author_facet | Oya Topaloglu Bekir Ucan Taner Demirci Muyesser Sayki Arslan Guleser Saylam Evrim Onder Sinan Gultekin Alper Dilli Mustafa Sahin Erman Cakal Mustafa Ozbek Tuncay Delibasi |
| author_sort | Oya Topaloglu |
| collection | DOAJ |
| description | A 68-year-old man had a rapidly growing, painless neck mass, thought to be nodular goiter. Ultrasonography showed a giant, heterogeneous mass occupying the middle and superior poles and protruding outside of the left thyroid lobe. The results of the thyroid function tests were normal. Thyroid scintigraphy revealed a large hypoactive nodule in the left thyroid lobe. Complete surgical removal of tumor was performed and macroscopically demonstrated a well-demarked lesion outside the thyroid gland. Microscopically, the lesion was composed of fibroblast-like spindle cells in a patternless architecture and extensive stromal hyalinization. Immunohistochemistry showed positive reaction for CD34 in spindle cells and diffuse bcl-2 staining. The pathology was confirmed as solitary fibrous tumor. In the follow-up period after surgery, thyroid scintigraphy showed normal left thyroid lobe. Solitary fibrous tumor originated from or associated with thyroid gland is extremely rare. According to our knowledge, this is the first reported solitary fibrous tumor presenting like a cold thyroid nodule. This pathology must be considered for differential diagnosis of neck masses in the thyroid region. |
| format | Article |
| id | doaj-art-7d4eaa7aa48d4d79b2d554c265bed75a |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-7d4eaa7aa48d4d79b2d554c265bed75a2025-02-03T01:29:57ZengWileyCase Reports in Endocrinology2090-65012090-651X2013-01-01201310.1155/2013/805745805745Solitary Fibrous Tumor of Neck Mimicking Cold Thyroid Nodule in 99m Tc Thyroid ScintigraphyOya Topaloglu0Bekir Ucan1Taner Demirci2Muyesser Sayki Arslan3Guleser Saylam4Evrim Onder5Sinan Gultekin6Alper Dilli7Mustafa Sahin8Erman Cakal9Mustafa Ozbek10Tuncay Delibasi11Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Otorhinolaryngology, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Pathology, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Nuclear Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Endocrinology and Metabolism, Ankara University School of Medicine, 06450 Ankara, TurkeyDepartment of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyDepartment of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Training and Research Hospital, 06130 Ankara, TurkeyA 68-year-old man had a rapidly growing, painless neck mass, thought to be nodular goiter. Ultrasonography showed a giant, heterogeneous mass occupying the middle and superior poles and protruding outside of the left thyroid lobe. The results of the thyroid function tests were normal. Thyroid scintigraphy revealed a large hypoactive nodule in the left thyroid lobe. Complete surgical removal of tumor was performed and macroscopically demonstrated a well-demarked lesion outside the thyroid gland. Microscopically, the lesion was composed of fibroblast-like spindle cells in a patternless architecture and extensive stromal hyalinization. Immunohistochemistry showed positive reaction for CD34 in spindle cells and diffuse bcl-2 staining. The pathology was confirmed as solitary fibrous tumor. In the follow-up period after surgery, thyroid scintigraphy showed normal left thyroid lobe. Solitary fibrous tumor originated from or associated with thyroid gland is extremely rare. According to our knowledge, this is the first reported solitary fibrous tumor presenting like a cold thyroid nodule. This pathology must be considered for differential diagnosis of neck masses in the thyroid region.http://dx.doi.org/10.1155/2013/805745 |
| spellingShingle | Oya Topaloglu Bekir Ucan Taner Demirci Muyesser Sayki Arslan Guleser Saylam Evrim Onder Sinan Gultekin Alper Dilli Mustafa Sahin Erman Cakal Mustafa Ozbek Tuncay Delibasi Solitary Fibrous Tumor of Neck Mimicking Cold Thyroid Nodule in 99m Tc Thyroid Scintigraphy Case Reports in Endocrinology |
| title | Solitary Fibrous Tumor of Neck Mimicking Cold Thyroid Nodule in 99m Tc Thyroid Scintigraphy |
| title_full | Solitary Fibrous Tumor of Neck Mimicking Cold Thyroid Nodule in 99m Tc Thyroid Scintigraphy |
| title_fullStr | Solitary Fibrous Tumor of Neck Mimicking Cold Thyroid Nodule in 99m Tc Thyroid Scintigraphy |
| title_full_unstemmed | Solitary Fibrous Tumor of Neck Mimicking Cold Thyroid Nodule in 99m Tc Thyroid Scintigraphy |
| title_short | Solitary Fibrous Tumor of Neck Mimicking Cold Thyroid Nodule in 99m Tc Thyroid Scintigraphy |
| title_sort | solitary fibrous tumor of neck mimicking cold thyroid nodule in 99m tc thyroid scintigraphy |
| url | http://dx.doi.org/10.1155/2013/805745 |
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