Identification and verification of XDH genes in ROS induced oxidative stress response of osteoarthritis based on bioinformatics analysis

Identification and verification of XDH genes in ROS induced oxidative stress response of osteoarthritis based on bioinformatics analysis

Abstract The purpose of this study was to search for genes related to ros induced oxidative stress in osteoarthritis(OA) cartilage through bioinformatics analysis, and to verify the expression of related genes in articular cartilage of OA patients. OA expression data and ROS-related genes were downl...

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Bibliographic Details
Main Authors: Chengze Qiu, Zhiyong Zhang, Haocheng Wang, Na Liu, Ruixin Li, Zhiheng Wei, Benjie Wang, Nan Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Osteoarthritis
Reactive oxygen species(ROS)
Oxidative stress
Xanthine dehydrogenase(XDH)
Bioinformatics analysis
Online Access:https://doi.org/10.1038/s41598-025-11667-7
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https://doi.org/10.1038/s41598-025-11667-7

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