Design, synthesis, in silico studies and antiproliferative evaluation of some novel hybrids of pyrimidine-morpholine

Design, synthesis, in silico studies and antiproliferative evaluation of some novel hybrids of pyrimidine-morpholine

IntroductionCancer is a complex group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body. These cells can invade nearby tissues and organs, or they may metastasize to other parts of the body through the bloodstream or lymphatic system.MethodsIn this study,...

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Main Authors: Elaheh Ataollahi, Leila Emami, Al-Anood Mohammad Al-Dies, Fateme Zare, Alireza Poustforoosh, Mina Emami, Fateme Saadat, Fateme Motamen, Zahra Rezaei, Soghra Khabnadideh
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Chemistry
Subjects:
pyrimidine
morpholine
synthesis
simulation
DNA
cytotoxic
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1537261/full
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https://www.frontiersin.org/articles/10.3389/fchem.2025.1537261/full

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