Drug-induced cytotoxicity prediction in muscle cells, an application of the Cell Painting assay.
In silico toxicity prediction offers the chance of reducing or replacing most animal testing through the integration of large experimental assay datasets with the appropriate computational approaches. The use of Cell Painting to detect various phenotypic changes induced by chemicals is emerging as a...
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| Main Authors: | Roman Lambert, Eva Serrano Candelas, Pablo Aparicio, Aisling Murphy, Rafael Gozalbes, Howard Oliver Fearnhead |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0320040 |
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