Drug-induced cytotoxicity prediction in muscle cells, an application of the Cell Painting assay.

In silico toxicity prediction offers the chance of reducing or replacing most animal testing through the integration of large experimental assay datasets with the appropriate computational approaches. The use of Cell Painting to detect various phenotypic changes induced by chemicals is emerging as a...

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Bibliographic Details
Main Authors: Roman Lambert, Eva Serrano Candelas, Pablo Aparicio, Aisling Murphy, Rafael Gozalbes, Howard Oliver Fearnhead
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0320040
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