Genome-wide screening and validation of exosome-derived TLN1 as a regulator of epithelial–mesenchymal transition in lung cancer

Genome-wide screening and validation of exosome-derived TLN1 as a regulator of epithelial–mesenchymal transition in lung cancer

Abstract In addition to embryonic development, wound healing, and tissue fibrosis, epithelial–mesenchymal transition (EMT) is another process that enhances tumor invasiveness and metastatic activity. Exosomes transport a variety of bioactive components between cells and are crucial for cell‒cell com...

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Bibliographic Details
Main Authors: Xianhui Ruan, Xing Wan, Weike Ma, Jianli Liu, Tongfei Tian, Jiaojiao Zhang, Jingtai Zhi, Minghan Qiu, Min Zhao, Qi Wang, Peng Li
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Epithelial–mesenchymal transition
Exosome
Lung cancer
Data integration
Cancer diagnosis
Online Access:https://doi.org/10.1038/s41598-025-96210-4
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https://doi.org/10.1038/s41598-025-96210-4

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