Nodal-dependent mesendoderm specification requires the combinatorial activities of FoxH1 and Eomesodermin.

Vertebrate mesendoderm specification requires the Nodal signaling pathway and its transcriptional effector FoxH1. However, loss of FoxH1 in several species does not reliably cause the full range of loss-of-Nodal phenotypes, indicating that Nodal signals through additional transcription factors durin...

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Bibliographic Details
Main Authors: Christopher E Slagle, Tsutomu Aoki, Rebecca D Burdine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002072&type=printable
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