Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial

Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial

Abstract Background More efficacious, noninvasive screening methods are needed for advanced colorectal neoplasia. miR-92a is a reliable and reproducible biomarker for early colorectal cancer detection in stool samples. We compared the diagnostic efficacies of miR-92a, immunochemical fecal occult blo...

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Main Authors: Jia-Chen Wang, Li Zhao, Xiang-Yang Yu, Ting-Ping Wu, Chang-Fa Xia, Ju-Fang Shi, Hui He, Zhi-Qi Chen, Dan Shi, Han Xue, Qi Ao, Shu-Ping Liao, Zhang-Qiang Zheng, Qiong-Fang Huang, Lin Li, Sui-Ling Lin, Ying-Xue Li, Wen-Long Hu, Ji Peng, Lin Lei, Mao-Mao Cao, Fan Yang, Xin-Xin Yan, Si-Yi He, Meng-Di Cao, Shao-Li Zhang, Yi Teng, Qian-Ru Li, Nuo-Pei Tan, Hao-Yang Yu, Hong-Hui Cheng, Xi-Mo Wang, Wei-Qing Wu, Wan-Qing Chen
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Military Medical Research
Subjects:
Advanced neoplasia
Colorectal cancer
Immunochemical fecal occult blood testing
MiR-92a
Screening
Online Access:https://doi.org/10.1186/s40779-025-00613-3
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https://doi.org/10.1186/s40779-025-00613-3

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