Pharmacokinetics and Tolerability of Δ9-THC-Hemisuccinate in a Suppository Formulation as an Alternative to Capsules for the Systemic Delivery of Δ9-THC

The objectives of this study were: (1) to assess the safety, tolerability, and pharmacokinetics of ascending doses of Δ9-tetrahydrocannabinol-hemisuccinate (THC-HS) after rectal administration as suppositories in male volunteers; and (2) to compare the pharmacokinetics of oral administrat...

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Bibliographic Details
Main Authors: Mahmoud A. ElSohly, Waseem Gul, Larry A. Walker
Format: Article
Language:English
Published: Karger Publishers 2018-06-01
Series:Medical Cannabis and Cannabinoids
Online Access:https://karger.com/article/doi/10.1159/000489037
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