Crude extracts from Diospyros gilletii stem bark attenuate Shigella flexneri-induced diarrhea in mice

Crude extracts from Diospyros gilletii stem bark attenuate Shigella flexneri-induced diarrhea in mice

Objective: To evaluate the anti-shigellosis activity of the hydroethanol extract of Diospyros gilletii (D. gilletii) stem bark in Shigella flexneri (S. flexneri)-induced diarrheal mice. Methods: The hydroethanolic extract was obtained by maceration of D. gilletii stem bark in 70% hydroethanol (water...

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Main Authors: Bijou-Lafortune Noumboue Kouamou, Boniface Pone Kamdem, Vincent Ngouana, Tashie Evangeline Ngwanguong, Jaurès Marius Tsakem Nangap, Listone Monelle Nzeye Ngameni, Yanick Kevin Dongmo Melogmo, Paul Keilah Lunga, Fabrice Fekam Boyom
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-06-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
diospyros gilletti
shigella flexneri
diarrhea
pro-inflammatory cytokines
acute toxicity
shigellosis
Online Access:https://journals.lww.com/10.4103/apjtb.apjtb_713_24
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https://journals.lww.com/10.4103/apjtb.apjtb_713_24

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