Two isoforms of the mRNA binding protein IGF2BP2 are generated by alternative translational initiation.

IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Polymorphisms in the Igf2bp2 gene are associated with risk of developing type 2 diabet...

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Bibliographic Details
Main Authors: Hang T T Le, Alice M Sorrell, Kenneth Siddle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0033140&type=printable
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