Structure of the lens MP20 mediated adhesive junction

Abstract Human lens fiber membrane intrinsic protein MP20 is the second most abundant membrane protein of the human eye lens. Despite decades of effort its structure and function remained elusive. Here, we determined the MicroED structure of full-length human MP20 in lipidic-cubic phase to a resolut...

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Bibliographic Details
Main Authors: William J. Nicolas, Anna Shiriaeva, Michael W. Martynowycz, Angus C. Grey, Yasmeen N. Ruma, Paul J. Donaldson, Tamir Gonen
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57903-6
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