Structural insights into polymerase-catalyzed FAD capping of hepatitis C virus RNA
Abstract The RNA polymerase NS5B of HCV is capable of catalyzing the addition of flavin adenine dinucleotide (FAD) to its RNA as a 5′ cap structure, aiding the virus in evading host immune responses. However, the exact mechanism underlying the 5′-FAD capping process of HCV RNA remains to be elucidat...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-62609-w |
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