Clinical outcome and genomic biomarkers of immune checkpoint inhibitor-based therapies for cancer of unknown primary: a multicenter, real-world study

Abstract Background Given the limited treatment options recommended for cancer of unknown primary (CUP), especially the role of immune checkpoint inhibitors (ICIs), our study aimed to evaluate the efficacy of ICIs and identify associated genomic biomarkers in these patients. Methods This retrospecti...

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Bibliographic Details
Main Authors: Yunjie Huang, Riqing Huang, Meiting Chen, Zhousan Zheng, Haifeng Li, Rishang Chen, Tinghua Gao, Ditian Shu, Anqi Hu, Qiufan Zheng, Xin An, Yanxia Shi, Cong Xue
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Journal of Cancer Research and Clinical Oncology
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Online Access:https://doi.org/10.1007/s00432-025-06261-3
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