The hepatocyte traffic network in the human hepatitis A virus biological cycle from an evolutionary perspective

The hepatocyte traffic network in the human hepatitis A virus biological cycle from an evolutionary perspective

Abstract Hepatitis A virus (HAV) egresses from hepatocytes cloaked in exosomes (eHAV). However, the traffic network used for its release from polarized hepatocytes is not completely understood. We propose that eHAV biogenesis may follow not only an ESCRT-mediated pathway but also the syndecan-synten...

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Main Authors: Albert Carcereny, Alba Arrebola, Gemma Chavarria-Miró, Montserrat de Castellarnau, Cristina Fuentes, David Garcia-Pedemonte, Adán Martínez-Velázquez, Enric Ribes, Albert Bosch, Susana Guix, Maria Isabel Costafreda, Rosa M. Pintó
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08344-w
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https://doi.org/10.1038/s42003-025-08344-w

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