In utero exposure to experimental maternal asthma alters fetal airway development in sheep

In utero exposure to experimental maternal asthma alters fetal airway development in sheep

Abstract The mechanisms linking maternal asthma (MA) exposure in utero and subsequent risk of asthma in childhood are not fully understood. Pathological airway remodelling, including reticular basement membrane thickening, has been reported in infants and children who go on to develop asthma later i...

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Main Authors: Sarah J. Hammond, Andrea J. Roff, Joshua L. Robinson, Jack R. T. Darby, Ashley S. Meakin, Vicki L. Clifton, Robert J. Bischof, Michael J. Stark, Megan J. Wallace, Andrew Tai, Janna L. Morrison, Kathryn L. Gatford
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Experimental Physiology
Subjects:
airway remodelling
asthma susceptibility
maternal asthma
pregnancy
respiratory development
sheep
Online Access:https://doi.org/10.1113/EP092502
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https://doi.org/10.1113/EP092502

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