Diagnosis and Pharmacological Management of Small Intestinal Bacterial Overgrowth in Children with Intestinal Failure

The present article provides a general overview of the possible diagnostic procedures available for the management of small intestinal bacterial overgrowth in pediatric patients with intestinal failure. The focus is to address current diagnostic tools and understand their associated advantages and d...

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Main Authors: Bushra A Malik, Yuan Y Xie, Eytan Wine, Hien Q Huynh
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2011/604643
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author Bushra A Malik
Yuan Y Xie
Eytan Wine
Hien Q Huynh
author_facet Bushra A Malik
Yuan Y Xie
Eytan Wine
Hien Q Huynh
author_sort Bushra A Malik
collection DOAJ
description The present article provides a general overview of the possible diagnostic procedures available for the management of small intestinal bacterial overgrowth in pediatric patients with intestinal failure. The focus is to address current diagnostic tools and understand their associated advantages and disadvantages based on a literature search. Culture of small intestinal aspirates, noninvasive breath tests and an emerging interest in quantitative bacterial DNA fingerprinting are discussed. Proper management is critical for preventing the recurrence of small intestinal bacterial overgrowth and its related complications. Antibiotic prophylaxis is one approach to the treatment of bacterial overgrowth in intestinal failure patients. Although treatment trials can be challenging in such a vulnerable population, more investigative clinical studies examining early diagnosis, more effective control of recurrence and the prevention of associated complications must be conducted.
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institution Kabale University
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publishDate 2011-01-01
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series Canadian Journal of Gastroenterology
spelling doaj-art-7c0eaa2aabec4ea5808a84061270a9832025-02-03T05:51:18ZengWileyCanadian Journal of Gastroenterology0835-79002011-01-01251414510.1155/2011/604643Diagnosis and Pharmacological Management of Small Intestinal Bacterial Overgrowth in Children with Intestinal FailureBushra A Malik0Yuan Y Xie1Eytan Wine2Hien Q Huynh3Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Stollery Children’s Hospital, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaDivision of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Stollery Children’s Hospital, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaDivision of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Stollery Children’s Hospital, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaDivision of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Stollery Children’s Hospital, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaThe present article provides a general overview of the possible diagnostic procedures available for the management of small intestinal bacterial overgrowth in pediatric patients with intestinal failure. The focus is to address current diagnostic tools and understand their associated advantages and disadvantages based on a literature search. Culture of small intestinal aspirates, noninvasive breath tests and an emerging interest in quantitative bacterial DNA fingerprinting are discussed. Proper management is critical for preventing the recurrence of small intestinal bacterial overgrowth and its related complications. Antibiotic prophylaxis is one approach to the treatment of bacterial overgrowth in intestinal failure patients. Although treatment trials can be challenging in such a vulnerable population, more investigative clinical studies examining early diagnosis, more effective control of recurrence and the prevention of associated complications must be conducted.http://dx.doi.org/10.1155/2011/604643
spellingShingle Bushra A Malik
Yuan Y Xie
Eytan Wine
Hien Q Huynh
Diagnosis and Pharmacological Management of Small Intestinal Bacterial Overgrowth in Children with Intestinal Failure
Canadian Journal of Gastroenterology
title Diagnosis and Pharmacological Management of Small Intestinal Bacterial Overgrowth in Children with Intestinal Failure
title_full Diagnosis and Pharmacological Management of Small Intestinal Bacterial Overgrowth in Children with Intestinal Failure
title_fullStr Diagnosis and Pharmacological Management of Small Intestinal Bacterial Overgrowth in Children with Intestinal Failure
title_full_unstemmed Diagnosis and Pharmacological Management of Small Intestinal Bacterial Overgrowth in Children with Intestinal Failure
title_short Diagnosis and Pharmacological Management of Small Intestinal Bacterial Overgrowth in Children with Intestinal Failure
title_sort diagnosis and pharmacological management of small intestinal bacterial overgrowth in children with intestinal failure
url http://dx.doi.org/10.1155/2011/604643
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AT hienqhuynh diagnosisandpharmacologicalmanagementofsmallintestinalbacterialovergrowthinchildrenwithintestinalfailure