A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.

A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.

A genomic signature for endosporulation includes a gene coding for a protease, YabG, which in the model organism Bacillus subtilis is involved in assembly of the spore coat. We show that in the human pathogen Clostridioidesm difficile, YabG is critical for the assembly of the coat and exosporium lay...

Full description

Saved in:
Bibliographic Details
Main Authors: Eleonora Marini, Carmen Olivença, Sara Ramalhete, Andrea Martinez Aguirre, Patrick Ingle, Manuel N Melo, Wilson Antunes, Nigel P Minton, Guillem Hernandez, Tiago N Cordeiro, Joseph A Sorg, Mónica Serrano, Adriano O Henriques
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011741&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011741&type=printable

Similar Items