Low-Dose Quercetin Dephosphorylates AKT and Suppresses Proteins Related to Migration in Human Metastatic Uveal Melanoma Cells

Low-Dose Quercetin Dephosphorylates AKT and Suppresses Proteins Related to Migration in Human Metastatic Uveal Melanoma Cells

<b>Background:</b> Uveal melanoma (UM) is the most common intraocular cancer of the eye, with high metastatic potential in adults. In 50% of patients, UM spreads to other tissues, causing a fatal outcome. Flavonoids are bioactive phenolic compounds found in fruits and plants, thus common...

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Main Authors: Petra Fodor, József Király, Zsuzsanna Szabó, Katalin Goda, Barbara Zsebik, Gábor Halmos
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Life
Subjects:
uveal melanoma
quercetin
metastasis
migration markers
epithelial–mesenchymal transition
Online Access:https://www.mdpi.com/2075-1729/15/6/979
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