Effect of IGHV Gene Mutation Status and BCR Structure Stereotypy on Effectiveness of BR Regimen in First-Line Therapy of Chronic Lymphocytic Leukemia

Effect of IGHV Gene Mutation Status and BCR Structure Stereotypy on Effectiveness of BR Regimen in First-Line Therapy of Chronic Lymphocytic Leukemia

Background & Aims. The IGHV gene mutation status is a constant biological feature of tumor cells in chronic lymphocytic leukemia (CLL). This parameter is an important predictor of the efficacy of immunochemotherapy. It was included into the CLL international prognostic index CLL-IPI developed re...

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Bibliographic Details
Main Authors: VV Strugov, EA Stadnik, AM Rumyantsev, TO Andreeva, YuV Virts, YuV Mirolyubova, PA Butylin, AYu Zaritskey
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2017-04-01
Series:Клиническая онкогематология
Subjects:
chronic lymphocytic leukemia
CLL
bendamustine
rituximab
BR
IGHV
mutation status
Online Access:http://bloodjournal.ru/wp-content/uploads/2017/03/2.pdf
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