Circular RNA HIPK3 mediates epithelial–mesenchymal transition of retinal pigment epithelial cells by sponging multiple microRNAs

Circular RNA HIPK3 mediates epithelial–mesenchymal transition of retinal pigment epithelial cells by sponging multiple microRNAs

Abstract Epithelial–mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells plays key roles in the pathogenesis of multiple vitreoretinal diseases, leading to profound and permanent vision loss. Circular RNAs (circRNAs) are widespread and functional endogenous RNAs that could regulate...

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Bibliographic Details
Main Authors: Yalan Feng, Fan Yang, Jijia Zheng, Lijun Shi, Tianhua Xie, Yunzhi Lin, Qian Shi
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Retinal pigment epithelium
circHIPK3
Epithelial–mesenchymal transition
Competing endogenous RNA
MicroRNAs
Online Access:https://doi.org/10.1038/s41598-024-71119-6
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https://doi.org/10.1038/s41598-024-71119-6

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