Multienzyme cascade for synthesis of hydroxytyrosol via engineered Escherichia coli

Multienzyme cascade for synthesis of hydroxytyrosol via engineered Escherichia coli

Abstract Hydroxytyrosol, a fine chemical, is widely utilized in food and pharmaceutical industries. In this study, we constructed a pathway to produce hydroxytyrosol by co-expressing tyrosin-phenol lyase (TPL), L-amino acid dehydrogenase (aadL), α-keto acid decarboxylase (KAD), aldehyde reductase (y...

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Bibliographic Details
Main Authors: Tianzhen Xiong, Xinmeng Li, Wei Liu, Huidie Yue, Junling Liu, Dingyuan Bai, Wei Li, Guangyan Fan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Hydroxytyrosol
Escherichia coli
Cascade reaction
Whole cell biotransformation
Online Access:https://doi.org/10.1038/s41598-024-84624-5
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https://doi.org/10.1038/s41598-024-84624-5

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