Effects of trace element dysregulation on brain structure and function in spinocerebellar Ataxia type 3

Effects of trace element dysregulation on brain structure and function in spinocerebellar Ataxia type 3

Spinocerebellar ataxia type 3 (SCA3), a neurodegenerative disorder caused by excess CAG repeats in the ATXN3 gene, leads to progressive cerebellar ataxia and other symptoms. The results of previous studies suggest that trace element dysregulation contributes to neurodegenerative disorder onset. Here...

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Bibliographic Details
Main Authors: LiHua Deng, Liu Feng, JingWen Li, YongHua Huang, PeiLing Ou, LinFeng Shi, Hui Chen, YuHan Zhang, LiMeng Dai, Yuan He, Chen Wei, HuaFu Chen, Jian Wang, Leinian Li, Chen Liu
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Neurobiology of Disease
Subjects:
Spinocerebellar ataxia type 3
Trace elements
Lithium
Diffusion tensor imaging (DTI)
fMRI
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996125000324
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