Dopamine modulates persistent synaptic activity and enhances the signal-to-noise ratio in the prefrontal cortex.

<h4>Background</h4>The importance of dopamine (DA) for prefrontal cortical (PFC) cognitive functions is widely recognized, but its mechanisms of action remain controversial. DA is thought to increase signal gain in active networks according to an inverted U dose-response curve, and these...

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Bibliographic Details
Main Authors: Sven Kroener, L Judson Chandler, Paul E M Phillips, Jeremy K Seamans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006507&type=printable
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