Stroma content in triple-negative breast cancer spheroid models regulates penetration and efficacy of tumor-targeting Salmonella typhimurium
Abstract Bacteria-based cancer therapy (BBCT) has not yet conferred clinical survival advantages in solid tumors, partly due to limited colonization. Collagen is well-known to hinder the penetration and efficacy of many therapeutic modalities in solid tumors. Nevertheless, the effect of collagen on...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
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| Series: | npj Breast Cancer |
| Online Access: | https://doi.org/10.1038/s41523-025-00770-7 |
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