Progressive subcortical involvement as spinocerebellar ataxia type 3 advances

Progressive subcortical involvement as spinocerebellar ataxia type 3 advances

Abstract Background and objectives Spinocerebellar ataxia type 3 (SCA3) is a progressive neurodegenerative disease characterized by heterogeneous motor and nonmotor manifestations. The progressive pattern of subcortical shape abnormalities and their associations with the clinical phenotypes in SCA3...

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Main Authors: Pubing Yuan, Yonghua Huang, Minghui Dai, Xin Jin, Dingxin Zheng, Die Xiao, Lihua Deng, Peiling Ou, Linfeng Shi, Yifan Chen, Jian Wang, Wei Chen, Yuanchao Zhang, Chen Liu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
FSL-FIRST
ATXN3
Spinocerebellar ataxia type 3 (SCA3)
Tract-based spatial statistics (TBSS)
Online Access:https://doi.org/10.1186/s13023-025-03803-3
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https://doi.org/10.1186/s13023-025-03803-3

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