Annexin-A1 deficiency uncovers female-specific pathways in blood pressure control and cardiovascular remodeling in mice

Annexin-A1 deficiency uncovers female-specific pathways in blood pressure control and cardiovascular remodeling in mice

Abstract Cardiovascular disease exhibits distinct sex-based differences, yet the mechanisms underlying these differences remain under-explored. The pro-resolving mediator annexin-A1 (ANXA1) is a pivotal regulator in inflammation resolution and tissue homeostasis, including within the cardiovascular...

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Main Authors: Jaideep Singh, Kristy L. Jackson, Haoyun Fang, Feng Shii Tang, Cindy Gueguen, Alex M. Parker, HsinErh Chen, Cameron J. Nowell, Helen Kiriazis, Ekaterina Salimova, Owen L. Woodman, Rebecca H. Ritchie, Geoffrey A. Head, David W. Greening, Cheng Xue Qin
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08291-6
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https://doi.org/10.1038/s42003-025-08291-6

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