MiR-21-5p enhances differentiation and mitigates oleic acid-induced lipid droplet accumulation in C2C12 myoblasts by targeting FBXO11

MiR-21-5p enhances differentiation and mitigates oleic acid-induced lipid droplet accumulation in C2C12 myoblasts by targeting FBXO11

Objective This study aimed to investigate the role of miRNA 21-5p in regulating the differentiation of C2C12 myoblasts and intramuscular lipid droplets accumulation in myotubes. Methods The role of miR-21-5p in the proliferation and differentiation of myofibroblasts and intracellular lipid accumulat...

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Bibliographic Details
Main Authors: Yi Li, Jiayuan Fang, Yingying Jiao, Qinchuan Lv, Xingyu Xiao, Shuo Zheng, Xi Chen, Jie Song, Xunming Zhang, Libo Zhang, Ze Ma, Changhong Li, Linlin Hao
Format: Article
Language:English
Published: Asian-Australasian Association of Animal Production Societies 2025-06-01
Series:Animal Bioscience
Subjects:
c2c12 myoblast
differentiation
fbxo11
intramuscular lipid deposition
mir-21-5p
proliferation
Online Access:http://www.animbiosci.org/upload/pdf/ab-24-0665.pdf
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http://www.animbiosci.org/upload/pdf/ab-24-0665.pdf

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