37-Day microgravity exposure in 16-Week female C57BL/6J mice is associated with bone loss specific to weight-bearing skeletal sites.

Exposure to weightlessness in microgravity and elevated space radiation are associated with rapid bone loss in mammals, but questions remain about their mechanisms of action and relative importance. In this study, we tested the hypothesis that bone loss during spaceflight in Low Earth Orbit is prima...

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Bibliographic Details
Main Authors: Rukmani Cahill, Elizabeth A Blaber, Cassandra M Juran, Margareth Cheng-Campbell, Joshua S Alwood, Yasaman Shirazi-Fard, Eduardo A C Almeida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0317307
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