PD-1-dependent therapeutic effect of Trichinella spiralis cystatin on myocardial infarction in a mice model

PD-1-dependent therapeutic effect of Trichinella spiralis cystatin on myocardial infarction in a mice model

Abstract Background Ischemia-induced inflammation is the primary pathological mechanism underlying cardiac tissue injury caused by myocardial infarction (MI). Trichinella spiralis cystatin (Ts-Cys) has been shown to regulate macrophage polarization and alleviate various inflammatory and immune-relat...

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Main Authors: Weixiao Zhang, Wenhui Yin, Hongtao Wang, Lingqin Wu, Chang Li, Xinyu Peng, Xiang Li, Kaibo Jiang, Huiqi Yang, Chenyue Dang, Erhe Gao, Qiwang Jin, Xiaodi Yang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Parasites & Vectors
Subjects:
Myocardial infarction
Macrophage
Trichinella spiralis
PD-1
Inflammation
Immunomodulation
Online Access:https://doi.org/10.1186/s13071-025-06854-4
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https://doi.org/10.1186/s13071-025-06854-4

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