Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry

Milkfish is the most produced finfish in the Philippines, with approximately 75 % of its fry sourced from hatcheries. Despite numerous studies on gut microbiota of wild and cultured fish species, the diversity and functional roles of the milkfish fry gut microbiome remain poorly understood. This stu...

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Main Authors: Gardel Xyza L. Silvederio, Therese F. Javellana, Ande Bryle N. Genciana, Maria Alexandra G. Fontanilla, Rex Ferdinand M. Traifalgar, Fredson H. Huervana, Carmelo S. del Castillo
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Journal of Genetic Engineering and Biotechnology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1687157X25000642
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author Gardel Xyza L. Silvederio
Therese F. Javellana
Ande Bryle N. Genciana
Maria Alexandra G. Fontanilla
Rex Ferdinand M. Traifalgar
Fredson H. Huervana
Carmelo S. del Castillo
author_facet Gardel Xyza L. Silvederio
Therese F. Javellana
Ande Bryle N. Genciana
Maria Alexandra G. Fontanilla
Rex Ferdinand M. Traifalgar
Fredson H. Huervana
Carmelo S. del Castillo
author_sort Gardel Xyza L. Silvederio
collection DOAJ
description Milkfish is the most produced finfish in the Philippines, with approximately 75 % of its fry sourced from hatcheries. Despite numerous studies on gut microbiota of wild and cultured fish species, the diversity and functional roles of the milkfish fry gut microbiome remain poorly understood. This study presents the first gut microbiome profiles of wild and hatchery-bred milkfish fry using 16S rRNA amplicon analysis. A total of 437 OTUs were recovered and significant differences in gut bacterial communities among fry from different sources was observed, indicating that habitat is a key determinant of gut microbiome diversity. The core gut microbiota analysis identified Vibrionaceae and Roseobacteraceae as the most common and abundant bacterial families across fry sources. However, Paenibacillaceae and Bacillaceae under Phylum Bacillota were dominant in wild fry sources, particularly Hamtic and Kirayan, whereas families belonging to Phyla Cyanobacteriota, and Thermodesulfobacteria were more prevalent in Dumagas and Kirayan hatchery fry sources. Functional predictions of the gut bacterial microbiome revealed 26 differentially abundant pathways between wild-caught and hatchery-bred fry, including those related to metabolism, organismal systems, cellular processes, environmental and genetic information processing. These findings highlight significant variations in gut microbiome composition, diversity, and functional potential across different sources of wild-caught and hatchery-bred fry. Understanding these source-specific microbial communities could provide insight into the development of interventions that can improve gut health and enhance milkfish hatchery practices. It can also generate information on ideal fry selection across local milkfish sources that will enhance larval productivity and survival in the succeeding nursery and grow-out culture stages.
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spelling doaj-art-7b97509b1e8740c1996d9e67e8239f342025-08-24T05:11:45ZengElsevierJournal of Genetic Engineering and Biotechnology1687-157X2025-09-0123310052010.1016/j.jgeb.2025.100520Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fryGardel Xyza L. Silvederio0Therese F. Javellana1Ande Bryle N. Genciana2Maria Alexandra G. Fontanilla3Rex Ferdinand M. Traifalgar4Fredson H. Huervana5Carmelo S. del Castillo6Institute of Fish Processing Technology, College of Fisheries and Ocean Sciences, University of the Philippines Visayas, Region, VI 5023, Philippines; Corresponding author.Institute of Aquaculture, College of Fisheries and Ocean Sciences, University of the Philippines Visayas, Region, VI 5023, PhilippinesInstitute of Aquaculture, College of Fisheries and Ocean Sciences, University of the Philippines Visayas, Region, VI 5023, PhilippinesInstitute of Aquaculture, College of Fisheries and Ocean Sciences, University of the Philippines Visayas, Region, VI 5023, PhilippinesInstitute of Aquaculture, College of Fisheries and Ocean Sciences, University of the Philippines Visayas, Region, VI 5023, PhilippinesInstitute of Aquaculture, College of Fisheries and Ocean Sciences, University of the Philippines Visayas, Region, VI 5023, PhilippinesInstitute of Aquaculture, College of Fisheries and Ocean Sciences, University of the Philippines Visayas, Region, VI 5023, Philippines; National Institute of Molecular Biology and Biotechnology, University of the Philippines Visayas, Region, VI 5023, PhilippinesMilkfish is the most produced finfish in the Philippines, with approximately 75 % of its fry sourced from hatcheries. Despite numerous studies on gut microbiota of wild and cultured fish species, the diversity and functional roles of the milkfish fry gut microbiome remain poorly understood. This study presents the first gut microbiome profiles of wild and hatchery-bred milkfish fry using 16S rRNA amplicon analysis. A total of 437 OTUs were recovered and significant differences in gut bacterial communities among fry from different sources was observed, indicating that habitat is a key determinant of gut microbiome diversity. The core gut microbiota analysis identified Vibrionaceae and Roseobacteraceae as the most common and abundant bacterial families across fry sources. However, Paenibacillaceae and Bacillaceae under Phylum Bacillota were dominant in wild fry sources, particularly Hamtic and Kirayan, whereas families belonging to Phyla Cyanobacteriota, and Thermodesulfobacteria were more prevalent in Dumagas and Kirayan hatchery fry sources. Functional predictions of the gut bacterial microbiome revealed 26 differentially abundant pathways between wild-caught and hatchery-bred fry, including those related to metabolism, organismal systems, cellular processes, environmental and genetic information processing. These findings highlight significant variations in gut microbiome composition, diversity, and functional potential across different sources of wild-caught and hatchery-bred fry. Understanding these source-specific microbial communities could provide insight into the development of interventions that can improve gut health and enhance milkfish hatchery practices. It can also generate information on ideal fry selection across local milkfish sources that will enhance larval productivity and survival in the succeeding nursery and grow-out culture stages.http://www.sciencedirect.com/science/article/pii/S1687157X25000642Gut microbiomeMilkfish fryWild-caughtHatchery-bredMicrobial diversityMetagenome
spellingShingle Gardel Xyza L. Silvederio
Therese F. Javellana
Ande Bryle N. Genciana
Maria Alexandra G. Fontanilla
Rex Ferdinand M. Traifalgar
Fredson H. Huervana
Carmelo S. del Castillo
Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry
Journal of Genetic Engineering and Biotechnology
Gut microbiome
Milkfish fry
Wild-caught
Hatchery-bred
Microbial diversity
Metagenome
title Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry
title_full Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry
title_fullStr Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry
title_full_unstemmed Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry
title_short Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry
title_sort gut microbiome composition and diversity of wild caught and hatchery bred milkfish chanos chanos fry
topic Gut microbiome
Milkfish fry
Wild-caught
Hatchery-bred
Microbial diversity
Metagenome
url http://www.sciencedirect.com/science/article/pii/S1687157X25000642
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